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Red Blood Cells vs. White Blood Cells: What's the Difference?

Medicine & HealthSide-by-sideWritten comparisonAll comparisons

Read the comparison below, or explore it visually. Create a visual lesson comparing red blood cells and white blood cells using available credits or plan allowance.

Red blood cells carry oxygen from the lungs to the body's tissues, while white blood cells defend the body against infection. Red cells are packed with the iron-rich protein haemoglobin and, in mammals, lose their nucleus to make room for it. White cells keep their nucleus, come in several types and are far fewer, with hundreds of red cells for every white cell.

At a glance

Red Blood CellsWhite Blood Cells
Main jobCarry oxygen and some carbon dioxideFight germs and clear damaged cells
NucleusNone in mature human red cellsPresent; shape varies by type
Shape and colourRed, biconcave disc about 7-8 micrometresColourless, irregular, mostly larger
Normal countRoughly 4-6 million per microlitre of bloodRoughly 4,000-11,000 per microlitre
LifespanAbout 120 daysHours to days; some memory cells for years

Which should you use?

Red Blood Cells

Red blood cells matter whenever oxygen delivery is the question, such as anaemia from iron deficiency, common in India, where too little haemoglobin leaves a person tired and breathless.

White Blood Cells

White blood cells matter whenever the body is fighting an invader, for example neutrophils gathering at an infected cut to form pus, or lymphocytes making antibodies after a vaccine.

Frequently asked questions

Where are red and white blood cells made?
Both are made from stem cells in the red bone marrow, found mainly in flat bones and the ends of long bones in adults. Some white cells, the lymphocytes, finish maturing in the thymus, lymph nodes and spleen.
Why do red blood cells have no nucleus?
Losing the nucleus frees space for more haemoglobin and lets the cell keep its flexible biconcave shape, which squeezes through narrow capillaries. The trade-off is that red cells cannot repair themselves, so they wear out in about 120 days.
What does a high white blood cell count mean?
A raised count often means the body is responding to an infection, inflammation or stress, but it can have other causes, including blood disorders. A blood test result outside the normal range needs to be interpreted by a doctor.