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Science

What is RNA?

RNA (ribonucleic acid) is a molecule that carries and acts on the genetic instructions stored in DNA. Its best-known form, messenger RNA, copies a gene's code and carries it to the cell's machinery to build proteins.

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Key things to understand

  • 1RNA is similar to DNA but single-stranded, and it uses the base uracil (U) instead of thymine (T).
  • 2Messenger RNA (mRNA) copies a gene and carries the instructions out of the nucleus.
  • 3Ribosomes read the mRNA to assemble proteins, the workhorses of the cell.
  • 4Other RNAs help build proteins and regulate genes, and some viruses use RNA as their genome.
  • 5mRNA vaccines use lab-made RNA to teach cells to make a harmless piece of a virus.

Frequently asked questions

What's the difference between DNA and RNA?
DNA is the long-term, double-stranded store of genetic information; RNA is a shorter-lived, usually single-stranded working copy that carries out tasks like building proteins.
How do mRNA vaccines work?
They deliver lab-made messenger RNA that instructs your cells to build a harmless piece of a virus, training your immune system to recognize the real thing.
Can RNA store genetic information like DNA?
Yes — some viruses, such as influenza and coronaviruses, use RNA as their genetic material instead of DNA.

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