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Science

What is A chromosome?

A chromosome is a tightly packaged structure of DNA and protein that carries an organism's genetic information. Humans have 46 chromosomes in most cells — 23 from each parent — organized so that very long DNA strands fit inside the nucleus.

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Watch a 2-minute lesson with voice + animation that explains a chromosome.
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Key things to understand

  • 1Each chromosome is one very long DNA molecule wound around proteins called histones.
  • 2Humans have 23 pairs (46 total); one pair (X and Y) is linked to biological sex.
  • 3Genes — the instructions for building proteins — are segments along the chromosomes.
  • 4Before a cell divides, each chromosome is copied so both new cells get a full set.
  • 5Errors in chromosome number or structure can cause genetic conditions.

Frequently asked questions

What's the difference between a gene, DNA, and a chromosome?
DNA is the molecule; a gene is a segment of DNA with instructions for a trait; a chromosome is a long DNA molecule packaged with protein. One chromosome contains many genes.
Why do humans have 46 chromosomes?
We inherit 23 from each parent. The number is simply how human genetic information is organized — other species have different counts.
What are X and Y chromosomes?
The sex chromosomes: typically two X's are associated with female development and an X and a Y with male development, though biology has exceptions.

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